doi: 10.1007/BF01641903.
Protection of mice against tick-borne encephalitis by different classes of immunoglobulins
- PMID: 689743
- DOI: 10.1007/BF01641903
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Protection of mice against tick-borne encephalitis by different classes of immunoglobulins
Infection.
1978.
Abstract
The protective capacities of IgM and IgG immunoglobulins from fractionated human or mouse sera were investigated in tests with tick-borne encephalitis virus. Mice were resistant to challenge with tick-borne encephalitis virus if previously inoculated with specific immunoglobulins but not nonspecific immunoglobulins. The protective ability of IgM, whether derived from mouse or human sera, was only about 1/40 of that of IgG preparations adjusted to the same haemagglutination inhibition or neutralising titres.
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