Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1981 Sep 11;9(17):4387-90.
doi: 10.1093/nar/9.17.4387.

The nucleotide sequence of the tRNAMMet from the archaebacterium Thermoplasma acidophilum

M W Kilpatrick, R T Walker

The nucleotide sequence of the tRNAMMet from the archaebacterium Thermoplasma acidophilum

M W Kilpatrick et al. Nucleic Acids Res. .

Abstract

Using in vitro labelling techniques, a tRNAMMet from Thermoplasma acidophilum, a member of the Archaebacteriae, has been shown to have the sequence: pGCCGGG Gs4UGGCUCANCUGGAGGAGC m2(2)GCCGGACmUCAUt6AAUCCGGAGGUCUCGGG psi psi CmGAUCCCCGAUCCCGGCACCAOH. Despite the small genome size of this non-parasitic organism, eight modified nucleosides are present, one of which is typically eubacterial, one of which is typically eukaryotic and some of which appear to be unique to the archaebacteria. There is no close sequence homology between this tRNA and that of any other methionine tRNA so far sequenced (less than 70%) but it has almost 90% homology with the nucleotide sequence proposed by Eigen and Oswatitsch for the ancestral quasi-species.

PubMed Disclaimer

References

    1. Nucleic Acids Res. 1977 Aug;4(8):2527-38 - PubMed
    1. Nucleic Acids Res. 1978 Jan;5(1):57-70 - PubMed
    1. Nature. 1978 Jul 6;274(5666):87-9 - PubMed
    1. Naturwissenschaften. 1981 May;68(5):217-28 - PubMed
    1. Science. 1980 Jul 25;209(4455):457-63 - PubMed

Publication types

Substances

Associated data