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. 1982 Aug;37(2):837-9.
doi: 10.1128/iai.37.2.837-839.1982.

Isolation and characterization of pneumolysin-negative mutants of Streptococcus pneumoniae

M K Johnson, D Hamon, G K Drew

Isolation and characterization of pneumolysin-negative mutants of Streptococcus pneumoniae

M K Johnson et al. Infect Immun. 1982 Aug.

Abstract

Pneumolysin-negative mutants of Streptococcus pneumoniae were isolated after mutagenesis with ethyl methane sulfonate. Though totally devoid of pneumolysin, these strains produced alpha hemolysis on blood agar when incubated aerobically. It is concluded that the alpha hemolysis typical of pneumococci is unrelated to their pneumolysin content.

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References

    1. J Bacteriol. 1980 Nov;144(2):698-709 - PubMed
    1. Infect Immun. 1972 Nov;6(5):755-60 - PubMed

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