doi: 10.1038/275501a0.
A two-step fibrinogen--fibrin transition in blood coagulation
- PMID: 692730
- DOI: 10.1038/275501a0
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A two-step fibrinogen--fibrin transition in blood coagulation
Nature.
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Abstract
The kinetics of the thrombin-catalysed release of fibrino-peptides A and B from human fibrinogen have been investigated and a mechanism correlating the release of fibrinopeptides to fibrin formation is presented. The sequential release of fibrinopeptides results in sequential activation of two sets of polymerisation sites.
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