The significance of some modifying factors during transplacental blastomogenesis by ethylnitrosourea in rabbits
- PMID: 692804
Item in Clipboard
The significance of some modifying factors during transplacental blastomogenesis by ethylnitrosourea in rabbits
Neoplasma.
1978.
Abstract
The development of the transplacental blastomogenesis induced by ethylnitrosourea (ENU) was studied in rabbits under the influence of modifying factors (organospecific immunity, chronic irradiation of the peripheral nerve, injection of methylnitrosourea -- MNU). Statistical analysis of the results showed that the postnatal immunization by the antigen prepared from homologous tissue of the peripheral nerve or its chronic irritation always stimulates the frequency of the tumors development. The injection of MNU inhibits the tumorigenesis in the tested animals. According to the data different modifying factors distinctly act upon the transplacental blastomogenesis in rabbits.
Similar articles
-
[Various aspects of transplacental blastomogenesis in rabbits].Biull Eksp Biol Med. 1978 Mar;85(3):343-6. Biull Eksp Biol Med. 1978. PMID: 96889 Russian.
-
[Significance of modifying factors in the development of peripheral nervous system tumors in rabbits].Vopr Onkol. 1978;24(9):60-5. Vopr Onkol. 1978. PMID: 706296 Russian.
-
Some results and prospects of transplacental carcinogenesis studies.Neoplasma. 1976;23(3):285-99. Neoplasma. 1976. PMID: 822360
-
Transplacental and neonatal induction of neurogenic tumors in mice: comparison with related species and with human pediatric neoplasms.Natl Cancer Inst Monogr. 1979 May;(51):219-26. Natl Cancer Inst Monogr. 1979. PMID: 384262 Review.
-
Fetal macrosomia and sex differences in the influence of modifying factors on transplacental carcinogenesis.IARC Sci Publ. 1989;(96):57-61. IARC Sci Publ. 1989. PMID: 2680957 Review.