Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1980 Apr;59(4):658-61.
doi: 10.1177/00220345800590040101.

Influence of alkaline pH on the effectiveness of sodium fluoride dentifrices

J Ennever, J K Peterson, W R Hester, V A Segreto, A W Radike
Clinical Trial

Influence of alkaline pH on the effectiveness of sodium fluoride dentifrices

J Ennever et al. J Dent Res. 1980 Apr.

Abstract

Two similar sodium fluoride dentifrices, one neutral and one alkaline, were compared to a placebo for clinical effectiveness in reducing caries. The neutral dentifrice contained 35% less soluble fluoride than the alkaline dentifrice. Both fluoride dentifrices were significantly effective but were not different from each other.

PubMed Disclaimer

LinkOut - more resources