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. 1980 Mar;77(3):1671-5.
doi: 10.1073/pnas.77.3.1671.

Choline accumulation by photoreceptor cells of the rabbit retina

R H Masland, J W Mills

Choline accumulation by photoreceptor cells of the rabbit retina

R H Masland et al. Proc Natl Acad Sci U S A. 1980 Mar.

Abstract

Photoreceptor cells of the rabbit retina accumulate choline from the extracellular environment by an overall process that has a high affinity for choline. These cells do not synthesize acetylcholine; instead, the choline taken up is incorporated into phosphorylcholine and eventually phospholipid. A mechanism for efficient choline accumulation is presumably concomitant to the photoreceptor cell's synthesis of large amounts of membrane for outer segment membrane renewal. Its existence in the photoreceptor cell supports previous evidence that high-affinity choline uptake is not confined to neurons that release acetylcholine, but may be present wherever large amounts of choline are required.

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References

    1. J Neurochem. 1976 Nov;27(5):999-1015 - PubMed
    1. J Neurochem. 1976 Nov;27(5):1017-25 - PubMed
    1. J Cell Biol. 1967 Apr;33(1):61-72 - PubMed
    1. J Cell Biol. 1968 Oct;39(1):169-84 - PubMed
    1. Adv Enzymol Relat Areas Mol Biol. 1967;29:1-32 - PubMed

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