Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Apr;77(4):1942-6.
doi: 10.1073/pnas.77.4.1942.

Multiple forms of H4 histone mRNA in human cells

A C Lichtler, S Detke, I R Phillips, G S Stein, J L Stein

Multiple forms of H4 histone mRNA in human cells

A C Lichtler et al. Proc Natl Acad Sci U S A. 1980 Apr.

Abstract

Two species of H4 histone mRNA were isolated from the polysomes of S phase HeLa S3 cells. Electrophoresis under denaturing and nondenaturing conditions indicates that the two H4 mRNAs differ in size. Both mRNAs translate H4 histones in vitro, lack poly(A) at their 3' termini, and are capped at their 5' termini. Polyacrylamide gel electrophoresis and tryptic peptide analysis suggest that the polypeptides synthesized by the two mRNAs are indistinguishable.

PubMed Disclaimer

References

    1. Biochem J. 1967 Nov;105(2):611-4 - PubMed
    1. Arch Biochem Biophys. 1969 Mar;130(1):337-46 - PubMed
    1. Nat New Biol. 1971 Apr 7;230(14):165-9 - PubMed
    1. J Cell Biol. 1972 Feb;52(2):292-307 - PubMed
    1. Nature. 1972 Nov 24;240(5378):225-8 - PubMed

Publication types

LinkOut - more resources