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. 1980 Oct;77(10):5580-2.
doi: 10.1073/pnas.77.10.5580.

Self-association and base pairing of guanosine, cytidine, adenosine, and uridine in dimethyl sulfoxide solution measured by 15N nuclear magnetic resonance spectroscopy

C Dyllick-Brenzinger, G R Sullivan, P P Pang, J D Roberts

Self-association and base pairing of guanosine, cytidine, adenosine, and uridine in dimethyl sulfoxide solution measured by 15N nuclear magnetic resonance spectroscopy

C Dyllick-Brenzinger et al. Proc Natl Acad Sci U S A. 1980 Oct.

Abstract

The self-association of guanosine, cytidine, and adenosine and base pairing between guanosine, cytidine, adenosine, and uridine in dimethyl sulfoxide have been investigated by the variation of their 15N NMR chemical shifts with concentration and temperature. Guanosine, cytidine, and adenosine all showed evidence of self-association by hydrogen bonding. In guanosine/cytidine mixtures, a hydrogen-bonded dimer is formed; however, no base pairing could be detected with adenosine/cytidine or adenosine/uridine mixtures.

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References

    1. J Mol Biol. 1966 Jan;15(1):220-31 - PubMed
    1. Biochem Biophys Res Commun. 1966 Apr 19;23(2):194-201 - PubMed
    1. J Am Chem Soc. 1968 Aug 28;90(18):5010-7 - PubMed
    1. J Am Chem Soc. 1968 Sep 11;90(19):5069-74 - PubMed
    1. J Am Chem Soc. 1977 Feb 2;99(3):714-8 - PubMed

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