doi: 10.1038/bjc.1980.145.
Bone tumours induced in rats with radioactive cerium
- PMID: 6932906
- PMCID: PMC2010306
- DOI: 10.1038/bjc.1980.145
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Bone tumours induced in rats with radioactive cerium
Br J Cancer.
1980 May.
Free PMC article
Abstract
A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours can be easily cultured and maintained by serial transplantations. Preliminary data of clinical, histological and kinetic characteristics of these bone tumours are given.
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