Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation
- PMID: 6933460
- PMCID: PMC349780
- DOI: 10.1073/pnas.77.7.4113
Monoclonal antibodies against trophectoderm-specific markers during mouse blastocyst formation
Abstract
Two-dimensional gel electrophoresis has allowed the detection of proteins characteristic of inner cell mass and trophectoderm in mouse blastocyst. Certain of the proteins characterizing trophectoderm copurify with intermediate filaments from trophectoderm and a trophoblastoma cell line. A monoclonal antibody prepared against proteins of these intermediate filaments labels a filament network in trophectoderm but not in inner cell mass cells.
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