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. 1980 Aug;77(8):5018-20.
doi: 10.1073/pnas.77.8.5018.

Enkephalin biosynthetic pathway: proteins of 8000 and 14,000 daltons in bovine adrenal medulla

R V Lewis, A S Stern, S Kimura, S Stein, S Udenfriend

Enkephalin biosynthetic pathway: proteins of 8000 and 14,000 daltons in bovine adrenal medulla

R V Lewis et al. Proc Natl Acad Sci U S A. 1980 Aug.

Abstract

Two [Met]enkephalin-containing polypeptides have been purified from extracts of bovine and adrenal chromaffin granules. One is 8000 daltons in size and contains the enkephalin sequence at the carboxy terminus. The other (14,000 daltons) has two internal enkephalin sequences and a third sequence at the carboxy terminus. All of these sequences can be released by trypsin, indicating a possible enkephalin precursor role for the polypeptides.

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References

    1. Arch Biochem Biophys. 1973 Mar;155(1):202-12 - PubMed
    1. Anal Biochem. 1975 Aug;67(2):438-45 - PubMed
    1. Methods Enzymol. 1977;47:335-57 - PubMed
    1. Brain Res. 1978 Jul 28;151(1):117-26 - PubMed
    1. Proc Natl Acad Sci U S A. 1979 Apr;76(4):1756-9 - PubMed

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