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. 1980 Oct;10(4):399-404.
doi: 10.1111/j.1365-2125.1980.tb01777.x.

Plasma kinetics and urinary excretion of primaquine in man

J Greaves, D A Evans, H M Gilles, K A Fletcher, D Bunnag, T Harinasuta

Plasma kinetics and urinary excretion of primaquine in man

J Greaves et al. Br J Clin Pharmacol. 1980 Oct.

Abstract

1 The kinetics of primaquine have been studied in twenty volunteers after single and multiple dose regimes. 2 The kinetic parameters were similar in glucose-6-phosphate dehydrogenase (G6PD) normal Thais, G6PD deficient Thais and in Caucasians. 3 The Caucasian subjects showed about 1% of the dose was excreted in the urine. 4 The kinetic parameters obtained from multiple dose studies in Thais were very similar to those obtained from single dose studies in Thais.

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