Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Nov;77(11):6764-8.
doi: 10.1073/pnas.77.11.6764.

Initial characterization of monoclonal antibodies against human monocytes

V Ugolini, G Nunez, R G Smith, P Stastny, J D Capra

Initial characterization of monoclonal antibodies against human monocytes

V Ugolini et al. Proc Natl Acad Sci U S A. 1980 Nov.

Abstract

Three monoclonal antibodies against human monocytes have been produced by somatic cell fusion. Extensive specificity analysis suggests that these antibodies react with most if not all human peripheral blood monocytes and not with highly purified T or B cells. Initial chemical characterization of the monocyte antigen recognized by two of these antibodies is presented. The molecule is a single polypeptide chain with an apparent molecular weight of 200,000. These reagents should prove useful in the clinical definition of disorders of monocyte differentiation, in studies of monocyte function, and in the elucidation of the genetics and structure of monocyte cell surface antigens.

PubMed Disclaimer

References

    1. J Exp Med. 1966 Aug 1;124(2):141-54 - PubMed
    1. Nature. 1968 Apr 6;218(5136):36-8 - PubMed
    1. Clin Exp Immunol. 1968 Oct;3(8):817-36 - PubMed
    1. Nature. 1970 Aug 15;227(5259):680-5 - PubMed
    1. J Exp Med. 1973 Oct 1;138(4):900-24 - PubMed

Publication types