Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Clinical Trial
. 1981 Feb;39(2):108-12.

An evaluation of the analgesic efficacy of three opioid-analgesic combinations in postoperative oral surgery pain

J A Forbes, M W Bowser, J P Calderazzo, V M Foor
  • PMID: 6936524
Clinical Trial

An evaluation of the analgesic efficacy of three opioid-analgesic combinations in postoperative oral surgery pain

J A Forbes et al. J Oral Surg. 1981 Feb.

Abstract

The analgesic efficacy of a hydrocodone-acetaminophen combination, a codeine-acetaminophen combination, a codeine-APC (aspirin, phenacetin, and caffeine) combination, and a placebo was evaluated in outpatients who had moderate or severe pain after the surgical removal of impacted third molars. Each of the active medications had a significant effect on essentially all measures of total and peak analgesia; they did not differ significantly on any measure of analgesia. Adverse effects were transitory and, in general, appear to have been related to the centrally acting component of each combination analgesic.

PubMed Disclaimer

Publication types