Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Mar;15(3):231-8.
doi: 10.1111/j.1399-0039.1980.tb00912.x.

Adult celiac disease associated with HLA-DRw3 and -DRw7

H Betuel, L Gebuhrer, L Descos, H Percebois, Y Minaire, J Bertrand

Adult celiac disease associated with HLA-DRw3 and -DRw7

H Betuel et al. Tissue Antigens. 1980 Mar.

Abstract

Celiac disease (CD), which occurs in Europe with varying frequency, is known to be associated with HLA-B8 and even more strongly with HLA-Dw3 because of the high linkage disequilibrium between these two antigens. After typing for HLA-A, -B and -DR antigens in adult patients with CD, we can confirm the high prevalence of B8 (72.7%) and of DRw3 (63.7%). However we find that DRw7 is also significantly increased (54.5%); DRw3 and DRw7, taken together, represent 86% of our 22 patients.

PubMed Disclaimer

Substances

LinkOut - more resources