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Comparative Study
. 1981 Jan;19(1):201-4.
doi: 10.1128/AAC.19.1.201.

N-formimidoyl thienamycin (MK0787): in vitro study

Comparative Study

N-formimidoyl thienamycin (MK0787): in vitro study

S Shadomy et al. Antimicrob Agents Chemother. 1981 Jan.

Abstract

N-Formimidoyl thienamycin (MK0787) was compared in vitro with three other beta-lactam and two aminoglycoside antibiotics. It was second in activity only to cefotaxime against members of the Enterobacteriaceae and to amikacin against Pseudomonas species. It was the most active antibiotic against Staphylococcus aureus. Resistance (minimal inhibitory concentration, greater than 128 microgram/ml) to N-formimidoyl thienamycin was not observed.

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