doi: 10.1073/pnas.78.6.3678.
Crystalline arrays of membrane-bound acetylcholine receptor
- PMID: 6943572
- PMCID: PMC319634
- DOI: 10.1073/pnas.78.6.3678
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Crystalline arrays of membrane-bound acetylcholine receptor
Proc Natl Acad Sci U S A.
1981 Jun.
Abstract
Electron micrographs of tubular structures with a crystalline arrangement of membrane-bound acetylcholine receptor oligomers have been analyzed by digital image reconstruction. The receptor molecules are oriented synaptic side out, and in projection they appear to be asymmetric and have a defined orientation. All four subunits are contained in the oligomers as demonstrated by immunoelectron microscopy; these structures therefore appear to be suitable for subunit localization in the oligomer.
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