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. 1981 Jun;78(6):3678-82.
doi: 10.1073/pnas.78.6.3678.

Crystalline arrays of membrane-bound acetylcholine receptor

J Kistler, R M Stroud

Crystalline arrays of membrane-bound acetylcholine receptor

J Kistler et al. Proc Natl Acad Sci U S A. 1981 Jun.

Abstract

Electron micrographs of tubular structures with a crystalline arrangement of membrane-bound acetylcholine receptor oligomers have been analyzed by digital image reconstruction. The receptor molecules are oriented synaptic side out, and in projection they appear to be asymmetric and have a defined orientation. All four subunits are contained in the oligomers as demonstrated by immunoelectron microscopy; these structures therefore appear to be suitable for subunit localization in the oligomer.

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References

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