Case Reports
doi: 10.1016/0165-4608(81)90088-1.
"Masked" philadelphia chromosome (Ph1) due to an unusual translocation
- PMID: 6945148
- DOI: 10.1016/0165-4608(81)90088-1
Item in Clipboard
Case Reports
"Masked" philadelphia chromosome (Ph1) due to an unusual translocation
Cancer Genet Cytogenet.
1981 Apr.
Abstract
The case of a 58-year-old white female with Philadelphia (Ph1)-positive chronic myelocytic leukemia (CML) and a "masked" Ph1 chromosome is described. The Ph1 was due to a translocation involving chromosomes #12 and #22, in which most of the long arm of #12 had been translocated to the deleted #22 (Ph1). The necessity of performing banding analysis in those cases of CML where a Ph1 is not readily apparent is stressed and the literature on"masked" Ph1 chromosomes is briefly summarized.
Similar articles
-
Variant Ph1 translocations in CML and their incidence, including two cases with sequential lymphoid and myeloid crises.Cancer Genet Cytogenet. 1982 Mar;5(3):187-201. doi: 10.1016/0165-4608(82)90025-5. Cancer Genet Cytogenet. 1982. PMID: 6950809
-
Masked Philadelphia chromosome caused by translocation (9;11;22).Cancer Genet Cytogenet. 1983 Apr;8(4):319-23. doi: 10.1016/0165-4608(83)90074-2. Cancer Genet Cytogenet. 1983. PMID: 6572552
-
Unusual translocations involving chromosomes 12;22 and 9;12 in a case of chronic myelogenous leukemia.Cancer Genet Cytogenet. 1985 Jan 1;14(1-2):61-5. doi: 10.1016/0165-4608(85)90215-8. Cancer Genet Cytogenet. 1985. PMID: 3855277
-
Chromosomes and causation of human cancer and leukemia. XXV. Significance of the Ph1 (including unusual translocations) in various acute leukemias.Cancer. 1977 Sep;40(3):1149-60. doi: 10.1002/1097-0142(197709)40:3<1149::aid-cncr2820400326>3.0.co;2-k. Cancer. 1977. PMID: 332321 Review.
-
Chronic myelogenous leukemia and genetic events at 9q34.Hematol Oncol. 1983 Jul-Sep;1(3):269-74. doi: 10.1002/hon.2900010309. Hematol Oncol. 1983. PMID: 6376316 Review.
Cited by
-
Translocations (4p+; 6q-) and (12q-; Xp+) in blastic phase of a Ph1-positive chronic myeloid leukemia.Blut. 1984 Oct;49(4):325-30. doi: 10.1007/BF00320206. Blut. 1984. PMID: 6593103
-
"Masked" Ph1-chromosome in chronic myelogenous leukaemia (CML).Blut. 1985 Mar;50(3):129-33. doi: 10.1007/BF00320068. Blut. 1985. PMID: 3856457
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
