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. 1981 Sep;78(9):5699-703.
doi: 10.1073/pnas.78.9.5699.

Lysosomal compartment of macrophages: extending the definition of GERL

P M Novikoff, A Yam, A B Novikoff

Lysosomal compartment of macrophages: extending the definition of GERL

P M Novikoff et al. Proc Natl Acad Sci U S A. 1981 Sep.

Abstract

"Professional phagocytes" such as Kupffer cells show an extensive network of interconnected residual bodies with cytochemically demonstrable acid phosphatase [orthophosphoric monoester phosphohydrolase (acid optimum), EC 3.1.3.2]. In such cells and in other (hepatocytes, etc.) this compartment may be considered a part of GERL [a hydrolase-rich region of endoplasmic reticulum (ER) situated at the trans face of the Golgi apparatus from which various Lysosomes appear to arise].

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