doi: 10.1002/1097-0142(197707)40:1<36::aid-cncr2820400108>3.0.co;2-7.
Expression of histocompatibility (HLA) antigens on tumor cells and normal cells from patients with melanoma
- PMID: 69483
- DOI: 10.1002/1097-0142(197707)40:1<36::aid-cncr2820400108>3.0.co;2-7
Item in Clipboard
Expression of histocompatibility (HLA) antigens on tumor cells and normal cells from patients with melanoma
Cancer.
1977 Jul.
Abstract
The expression of HLA antigens and beta2-microglobulin (beta2-mu) on cultured melanoma cells originated from 11 patients has been quantitated and compared with that on fibroblasts and cultured human lymphoid cells originated from the same patients. No qualitative or quantitative difference was detected with the exception of one melanoma line. HLA antigens were also quantitated in sera from melanoma patients: two sera reacted with anti-HLA-B7 antibodies although this specificity was not expressed on lymphocytes from whom the sera were obtained. A technique to quantitate HLA antigens on cells developed in the course of this study is described.
Similar articles
-
Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines.J Exp Med. 1978 Jul 1;148(1):58-70. doi: 10.1084/jem.148.1.58. J Exp Med. 1978. PMID: 78963 Free PMC article.
-
Association between HLA determinants and complement receptors on human lymphocytes.Tissue Antigens. 1977 Aug;10(2):99-107. doi: 10.1111/j.1399-0039.1977.tb01124.x. Tissue Antigens. 1977. PMID: 70864
-
Recombinant interferon-gamma can induce the expression of HLA-DR and -DC on DR-negative melanoma cells and enhance the expression of HLA-ABC and tumor-associated antigens.Eur J Immunol. 1985 Feb;15(2):118-23. doi: 10.1002/eji.1830150204. Eur J Immunol. 1985. PMID: 3918869
-
Beta2-microglobulin gene mutations in human melanoma cells: molecular characterization and implications for immune surveillance.Melanoma Res. 1997 Aug;7 Suppl 2:S67-74. Melanoma Res. 1997. PMID: 9578419 Review.
-
Preliminary amino acid sequences of transplantation antigens: genetic and evolutionary implications.Contemp Top Mol Immunol. 1976;5:35-68. doi: 10.1007/978-1-4684-8142-6_2. Contemp Top Mol Immunol. 1976. PMID: 63354 Review.
Cited by
-
Quantitative correlation between HLA class I allele expression and recognition of melanoma cells by antigen-specific cytotoxic T lymphocytes.Cancer Res. 1995 Jul 15;55(14):3149-57. Cancer Res. 1995. PMID: 7541714 Free PMC article.
-
Oncofoetal antigen I: a target for immune cytolysis of human cancer.Br J Cancer. 1979 Dec;40(6):950-3. doi: 10.1038/bjc.1979.291. Br J Cancer. 1979. PMID: 526435 Free PMC article. No abstract available.
-
In vitro production of human antibody to a tumour-associated foetal antigen.Br J Cancer. 1981 Aug;44(2):262-6. doi: 10.1038/bjc.1981.178. Br J Cancer. 1981. PMID: 7272192 Free PMC article. No abstract available.
-
Locus-specific analysis of human leukocyte antigen class I expression in melanoma cell lines.J Immunother Emphasis Tumor Immunol. 1994 Jul;16(1):13-23. doi: 10.1097/00002371-199407000-00002. J Immunother Emphasis Tumor Immunol. 1994. PMID: 8081556 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Research Materials