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. 1977 Jul 15;78(2):343-9.
doi: 10.1016/0009-8981(77)90326-6.

The determination of serum immunoglobulin concentrations on the basis of their light-chain antigenic properties

K Eickhoff, R Heipertz

The determination of serum immunoglobulin concentrations on the basis of their light-chain antigenic properties

K Eickhoff et al. Clin Chim Acta. .

Abstract

A method for the measurement of light-chain determined immunoglobulin concentrations (Ig-type kappa and Ig-type lambda) in serum is described. The method is based on the principle of radial immunodiffusion. The results obtained after calibration with standarized human serum and with isolated Bence-Jones protein are closely correlated. The values for Ig-type kappa, Ig-type lambda and the kappa/lambda ratio from sera with normal concentrations of IgG, IgA and IgM are presented and some problems of calibration discussed.

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