Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1982 Sep;79(17):5362-6.
doi: 10.1073/pnas.79.17.5362.

Mta, a maternally inherited cell surface antigen of the mouse, is transmitted in the egg

K F Lindahl, K Bürki

Mta, a maternally inherited cell surface antigen of the mouse, is transmitted in the egg

K F Lindahl et al. Proc Natl Acad Sci U S A. 1982 Sep.

Abstract

Mta is a maternally transmitted cell surface antigen found in most mouse strains. It serves as a target for unrestricted T killer cells. All 49 embryos transferred between positive and negative mothers, even as early as 10-15 hr after fertilization, developed into mice with the Mta type of their original mothers. Therefore the genetic element that determines expression of Mta must be transmitted by the egg. Mta+ and Mta- lymphocytes, coexisting for months in lethally irradiated F1 mice reconstituted with a mixture of parental bone marrow cells, retained their Mta type. Thus Mta does not spread by infection.

PubMed Disclaimer

References

    1. Biol Reprod. 1973 May;8(4):420-6 - PubMed
    1. J Immunol. 1980 Feb;124(2):533-40 - PubMed
    1. Eur J Immunol. 1979 Nov;9(11):875-86 - PubMed
    1. J Exp Med. 1980 May 1;151(5):1139-50 - PubMed
    1. Immunol Rev. 1979;47:175-206 - PubMed

Publication types

LinkOut - more resources