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. 1982 Dec;79(23):7460-4.
doi: 10.1073/pnas.79.23.7460.

Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2

D Meruelo, M Offer, A Rossomando

Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2

D Meruelo et al. Proc Natl Acad Sci U S A. 1982 Dec.

Abstract

The region of chromosome 2 between H-13 and H-3 has been shown to contain loci coding for a variety of other alloantigens, including Ly-4 and the locus coding for beta 2-microglobulin. Herein we show that Ly-6 and Ly-11 are coded for by genes in a segment of chromosome 2 adjacent to the H-3-H-13 region and that this segment of chromosome also contains the tightly linked loci coding for antigens Ala-1, DAG, H9/25, H-30, Ly-8, and ThB. In addition, at least one locus (and probably more) affecting susceptibility to leukemia induction is found within this gene cluster.

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