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. 1982 Dec;22(6):1079-81.
doi: 10.1128/AAC.22.6.1079.

In vitro susceptibility of Mycobacterium fortuitum to N-formimidoyl thienamycin and several cephamycins

In vitro susceptibility of Mycobacterium fortuitum to N-formimidoyl thienamycin and several cephamycins

M H Cynamon et al. Antimicrob Agents Chemother. 1982 Dec.

Abstract

The comparative in vitro activity of N-formimidoyl thienamycin, cefmetazole, cefoxitin, cefotetan (YM-09330), and moxalactam against 13 isolates of Mycobacterium fortuitum was evaluated by agar dilution susceptibility testing. N-Formimidoyl thienamycin inhibited 10 to 12 strains at 6.25 micrograms/ml, cefmetazole inhibited 12 of 13 strains at 12.5 micrograms/ml, cefoxitin inhibited 11 of 13 strains at 25 micrograms/ml, and cefotetan inhibited 11 of 13 strains at 50 micrograms/ml. Moxalactam was less active than the other compounds tested, inhibiting only 9 of 13 strains at 50 micrograms/ml.

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References

    1. Antimicrob Agents Chemother. 1977 Aug;12(2):295-7 - PubMed
    1. J Antimicrob Chemother. 1979 Nov;5(6):635-71 - PubMed
    1. Antimicrob Agents Chemother. 1981 Jan;19(1):205-7 - PubMed

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