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. 1980 Mar;124(3):1075-8.

Ia antigen on the surface of a subfraction of T cells that bear Fc receptors for IgG

P A Kaszubowski, J S Goodwin, R C Williams Jr
  • PMID: 6965684

Ia antigen on the surface of a subfraction of T cells that bear Fc receptors for IgG

P A Kaszubowski et al. J Immunol. 1980 Mar.

Abstract

Human peripheral blood T cells and T cell subpopulations were studied for the presence of Ia-like antigen, by using indirect immunofluorescence with heterologous rabbit anti-Ia antisera. In 13 normal subjects the percentage of T cells staining with the anti-Ia reagent was 2 to 5% and appeared limited to the T gamma subfraction. After concanavalin A (Con A) or phytohemagglutinin (PHA) activation, the proportion of Ia(+) T cells increased due to an increase in the percentage of T gamma cells bearing Ia-like antigen as well as an increase in the proportion of T gamma cells in the T cell fraction.

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