Intrahypothalamic terminals of stress conducting fibers

Abstract

Surgical stress did not elevate plasma corticosterone level in rats with bilateral surgical transection of the lateral retrochiasmatic area (RCAL). After RCAL transections light and electron microscopic terminal degeneration was observed in both the external and the internal layers of the median eminence as well as in the arcuate and ventromedial nuclei. Incisions lateral to the medial forebrain bundle did not prevent the stress-induced rise in plasma corticosterone level and were not followed by degeneration in the median eminence. Transection of the medial forebrain bundle rostral or caudal to the RCAL caused degeneration in both the median eminence and the arcuate nucleus.