Comparative Study
doi: 10.1111/j.1755-3768.1980.tb05741.x.
Lymphocyte subpopulations in peripheral blood and cerebrospinal fluid from patients with acute optic neuritis
- PMID: 6968144
- DOI: 10.1111/j.1755-3768.1980.tb05741.x
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Comparative Study
Lymphocyte subpopulations in peripheral blood and cerebrospinal fluid from patients with acute optic neuritis
Acta Ophthalmol (Copenh).
1980 Jun.
Abstract
Ten patients with acute optic neuritis (AON) were examined for T and B lymphocytes in blood and cerebrospinal fluid by means of rosette techniques. The percentage of T lymphocytes in blood was significantly decreased (54+/-3%) compared to controls (66+/-2%). Absolute numbers of T lymphocytes, and relative and absolute B lymphocyte concentrations were not significantly different from controls. The cerebrospinal fluid (CSF) T lymphocyte percentage was significantly increased (88.8% compared to 78.0% in controls). The relative CSF immunoglobulin G concentration was elevated in four patients (40%). On agarose gel electrophoresis, bands in the gamma globulin region were found in two patients (20%).
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