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. 1980 Oct;66(4):843-6.
doi: 10.1172/JCI109922.

Lymphocyte adherence to myelinated tissue in multiple sclerosis

P Dore-Duffy, V Goertz, B L Rothman

Lymphocyte adherence to myelinated tissue in multiple sclerosis

P Dore-Duffy et al. J Clin Invest. 1980 Oct.

Abstract

A small subpopulation of human peripheral blood T lymphocytes has the capacity to adhere selectively to myelinated sections of human and nonhuman brain tissue. Adherence of lymphocytes from patients with multiple sclerosis is significantly greater than adherence of control lymphocytes. Monocytes inhibit binding in controls. This function appears to be lost by multiple sclerosis monocytes.

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