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. 1980 Jul;103(1):67-72.
doi: 10.1111/j.1365-2133.1980.tb15839.x.

In situ identification and enumeration of T lymphocytes in cutaneous T-cell lymphomas by demonstration of granular activity of acid non-specific esterase

W Sterry, G K Steigleder, H Pullmann

In situ identification and enumeration of T lymphocytes in cutaneous T-cell lymphomas by demonstration of granular activity of acid non-specific esterase

W Sterry et al. Br J Dermatol. 1980 Jul.

Abstract

Activity of acid non-specific esterase (ANAE) in infiltrating lymphocytes in nine patients with mycosis fungoides and four patients with parapsoriasis en plaques was examined in frozen tissue sections. Within the dermal infiltrate 81.7 +/- 6.1% of all lymphocytes contain this enzyme in mycosis fungoides, 74.7 +/- 3.3% in parapsoriasis en plaques. These results correlate well with the percentage of T lymphocytes determined by immunological techniques. Mycosis fungoides may be regarded as an ANAE-positive cutaneous T-cell lymphoma. Because of its simplicity this technique may be of value in further investigations of mycosis fungoides.

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