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Comparative Study
. 1980;39(3):185-201.
doi: 10.1016/0022-1759(80)90055-1.

Biochemical separation of interleukin 2

D Y Mochizuki, J Watson, S Gillis
Comparative Study

Biochemical separation of interleukin 2

D Y Mochizuki et al. J Immunol Methods. 1980.

Abstract

Interleukin 2 (IL-2) is a class of T cell growth factors produced by T cells of a number of species. The unique growth-promoting properties of these molecules allow the development of antigen-specific effector T cell lines which can be used to analyze the molecular basis of lymphocyte interactions. A murine T cell tumor line has been identified as a source of IL-2. The purification and biochemical properties of murine IL-2 are described, and compared with rat and human Il-2.

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