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Comparative Study
. 1981 Mar;53(3):267-72.
doi: 10.1093/bja/53.3.267.

A study of three doses of ici 35 868 for induction and maintenance of anaesthesia

E Major, A J Verniquet, T K Waddell, T M Savege, D E Hoffler, W Aveling
Free article
Comparative Study

A study of three doses of ici 35 868 for induction and maintenance of anaesthesia

E Major et al. Br J Anaesth. 1981 Mar.
Free article

Abstract

Three doses (1.5, 2.0 and 2.5 mg kg-1) of diisopropyl phenol (ICI 35 868) were compared for induction and maintenance of anaesthesia in healthy females undergoing short gynaecological procedures. Induction of anaesthesia was smooth and rapid. Cardiovascular changes (which were dose-dependent) included a decrease in arterial pressure and an increase in heart rate. These changes were magnitudes comparable to those reported for other induction agents. Recovery from the effects of the drug was rapid and uneventful.

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