[On the pharmacokinetics of tiaprofenic acid and its possible interactions with acetylsalicylic acid and aluminum hydroxide (author's transl)]
- PMID: 6971108
[On the pharmacokinetics of tiaprofenic acid and its possible interactions with acetylsalicylic acid and aluminum hydroxide (author's transl)]
Abstract
To clarify the question whether pharmacokinetic properties of tiaprofenic acid (presumable trade name Surgam) can be changed by simultaneous application of aluminum hydroxide or acetylsalicylic acid (ASA) a randomized study of 7 healthy volunteers was carried out. The results show that the bioavailability as well as the pharmacokinetic profile of orally administered tiaprofenic acid is not changed by the mentioned compounds.
Similar articles
-
Clinical pharmacokinetics of tiaprofenic acid and its enantiomers.Clin Pharmacokinet. 1996 Nov;31(5):331-47. doi: 10.2165/00003088-199631050-00002. Clin Pharmacokinet. 1996. PMID: 9118583 Review.
-
[Study on possible interactions between tiaprofenic acid and phenprocoumon (author's transl)].Arzneimittelforschung. 1981;31(12):2163-7. Arzneimittelforschung. 1981. PMID: 7199320 German.
-
A comparative trial of tiaprofenic acid ('Surgam') versus aspirin in the control of pain following injury.Pharmatherapeutica. 1981;2(8):509-12. Pharmatherapeutica. 1981. PMID: 7019930 Clinical Trial.
-
Single dose pharmacokinetics of tiaprofenic acid. Effects of food and severe renal insufficiency.Arzneimittelforschung. 1985;35(5):871-5. Arzneimittelforschung. 1985. PMID: 4026912
-
Tiaprofenic acid.Clin Rheum Dis. 1984 Aug;10(2):333-51. Clin Rheum Dis. 1984. PMID: 6391794 Review. No abstract available.
Cited by
-
Pharmacokinetic drug interactions with nonsteroidal anti-inflammatory drugs.Clin Pharmacokinet. 1990 Jul;19(1):44-66. doi: 10.2165/00003088-199019010-00004. Clin Pharmacokinet. 1990. PMID: 2199127 Review.
-
Pharmacokinetics of tiaprofenic acid in elderly multimorbid patients.Drugs. 1988;35 Suppl 1:53-6. doi: 10.2165/00003495-198800351-00012. Drugs. 1988. PMID: 3359947 No abstract available.
-
Clinical pharmacokinetics of tiaprofenic acid and its enantiomers.Clin Pharmacokinet. 1996 Nov;31(5):331-47. doi: 10.2165/00003088-199631050-00002. Clin Pharmacokinet. 1996. PMID: 9118583 Review.
-
Effects of antacids on the clinical pharmacokinetics of drugs. An update.Clin Pharmacokinet. 1990 Mar;18(3):210-9. doi: 10.2165/00003088-199018030-00003. Clin Pharmacokinet. 1990. PMID: 1969784 Review.
-
Tiaprofenic acid. A review of its pharmacological properties and therapeutic efficacy in rheumatic diseases and pain states.Drugs. 1985 Mar;29(3):208-35. doi: 10.2165/00003495-198529030-00002. Drugs. 1985. PMID: 3886353 Review.