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. 1981 Mar 30;209(2):496-500.
doi: 10.1016/0006-8993(81)90177-3.

Reward and detection thresholds for brain stimulation: dissociative effects of cocaine

C Kornetsky, R U Esposito

Reward and detection thresholds for brain stimulation: dissociative effects of cocaine

C Kornetsky et al. Brain Res. .

Abstract

The effects of cocaine on both rewarding and detection thresholds for intracranial stimulation to the same brain sites in the same animals were determined. The drug caused a dissociation in effects on the two types of brain stimulation. Detection threshold was elevated at doses of cocaine that lowered the reward threshold.

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