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. 1977 Aug;23(2):315-22.
doi: 10.1128/JVI.23.2.315-322.1977.

Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells

J Ledbetter, R C Nowinski

Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells

J Ledbetter et al. J Virol. 1977 Aug.

Abstract

The Gross cell surface antigen (GCSA) is produced by cells that are either exogenously infected with murine leukemia virus (MuLV) or are expressing endogenous MuLV genomes. In immune precipitation assays, GCSA was resolved into two serologically distinct 85,000- and 95,000-dalton viral proteins. These antigenic components are glycosylated forms of the polyprotein precursors of the MuLV internal structural proteins.

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