[Animal experiments on cementing small osteochondral fragments with fibrin glue]

Abstract

An experiment on revascularization of glued osteochondral fragments was carried out. A chiseled part of the medial femoral condyle of the knee joint of the rabbit was fixed on the right side with an acryl adhesive and on the left side with a new fibrinogen adhesive system (FAS), consisting of highly concentrated fibrinogen, thrombin, and factor XIII. The animals were sacrificed after three, six, ten, and twenty eight days. The FAS is changed into granulation tissue rich in vessels and, therefore, there is a quick revascularization of the fragments soon after three days. On the contrary the acryl adhesive is a foreign body and prevents ingrowth of capillaries during the time of investigation. Immobilization with plaster is necessary to prevent the fragment from gliding off.