[Effect of serum against hematopoietic stem cells (RAMBS) on self-maintaining cells of Rauscher erythroleukemia]
[Article in
Russian]
- PMID: 6973375
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[Effect of serum against hematopoietic stem cells (RAMBS) on self-maintaining cells of Rauscher erythroleukemia]
[Article in
Russian]
Biull Eksp Biol Med.
1981 Apr.
Abstract
The spleen colony assay was used to study the effect of rabbit antimouse brain serum (RAMBS) on erythroleukemic colony-forming cells (ECFC). RAMBS was shown to specifically inactivate hemopoietic stem cells (CFU-S) and to have no influence on ECFC growth. Absorption of RAMBS by erythroleukemic cells did not inhibit its anti-CFU-S activity. It is suggested that CFU-S and ECFC differ in the antigenic spectrum.
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