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. 1981 Apr;91(4):476-8.

[Effect of serum against hematopoietic stem cells (RAMBS) on self-maintaining cells of Rauscher erythroleukemia]

[Article in Russian]
E B Mechetner, E N Rozinova
  • PMID: 6973375

[Effect of serum against hematopoietic stem cells (RAMBS) on self-maintaining cells of Rauscher erythroleukemia]

[Article in Russian]
E B Mechetner et al. Biull Eksp Biol Med. 1981 Apr.

Abstract

The spleen colony assay was used to study the effect of rabbit antimouse brain serum (RAMBS) on erythroleukemic colony-forming cells (ECFC). RAMBS was shown to specifically inactivate hemopoietic stem cells (CFU-S) and to have no influence on ECFC growth. Absorption of RAMBS by erythroleukemic cells did not inhibit its anti-CFU-S activity. It is suggested that CFU-S and ECFC differ in the antigenic spectrum.

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