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. 1981 Jul;78(7):4566-70.
doi: 10.1073/pnas.78.7.4566.

Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen

D A Shackelford, D L Mann, J J van Rood, G B Ferrara, J L Strominger

Human B-cell alloantigens DC1, MT1, and LB12 are identical to each other but distinct from the HLA-DR antigen

D A Shackelford et al. Proc Natl Acad Sci U S A. 1981 Jul.

Abstract

Some human B-lymphoblastoid cell lines are shown to express at least two types of Ia-like antigens. One antigen is defined by alloantisera to HLA-DR, and the other antigen is defined by alloantisera and a monoclonal antibody to the specificities DC1, MT1 (MB1), and LB12, which are in linkage disequilibrium with HLA-DR. The subunits of the DC1 molecule differ from those of the DR molecule. The light chains of both molecules are structurally polymorphic.

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