Case Reports
doi: 10.1111/j.1651-2227.1981.tb05742.x.
Immotile cilia syndrome: radial spokes deficiency in a patient with Kartagener's triad
- PMID: 6976061
- DOI: 10.1111/j.1651-2227.1981.tb05742.x
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Case Reports
Immotile cilia syndrome: radial spokes deficiency in a patient with Kartagener's triad
Acta Paediatr Scand.
1981 Jul.
Abstract
Mucociliary transport and ultrastructure of nasal cilia in a 13 year old boy with Kartagener's triad, were investigated. Mucociliary transport was significantly delayed (greater than 30 minutes). Electron microscopy showed cilia lacking radial spokes, eccentric central tubules, and a dislocation of one the outer doublets. Dynein arms were present. We consider the radial spoke defect as a distinct congenital anomaly which contributes to the pathogenesis of the "immotile cilia syndrome".
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