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Case Reports
. 1981 Jul;70(4):571-3.
doi: 10.1111/j.1651-2227.1981.tb05742.x.

Immotile cilia syndrome: radial spokes deficiency in a patient with Kartagener's triad

M Antonelli, A Modesti, M De Angelis, P Marcolini, N Lucarelli, S Crifo
Case Reports

Immotile cilia syndrome: radial spokes deficiency in a patient with Kartagener's triad

M Antonelli et al. Acta Paediatr Scand. 1981 Jul.

Abstract

Mucociliary transport and ultrastructure of nasal cilia in a 13 year old boy with Kartagener's triad, were investigated. Mucociliary transport was significantly delayed (greater than 30 minutes). Electron microscopy showed cilia lacking radial spokes, eccentric central tubules, and a dislocation of one the outer doublets. Dynein arms were present. We consider the radial spoke defect as a distinct congenital anomaly which contributes to the pathogenesis of the "immotile cilia syndrome".

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