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. 1981 Nov;12(5):701-3.
doi: 10.1111/j.1365-2125.1981.tb01293.x.

The effect of co-trimoxazole on serum creatinine

B A Dijkmans, J P van Hooff, F A de Wolff, H Mattie

The effect of co-trimoxazole on serum creatinine

B A Dijkmans et al. Br J Clin Pharmacol. 1981 Nov.

Abstract

1 Co-trimoxazole induces a highly significant and reversible elevation of the serum creatinine level. 2 In renal-allograft patients the degree of this elevation is significantly correlated with the concentration of serum creatinine before administration of co-trimoxazole and with the concentration of non-protein-bound trimethoprim.

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