This site needs JavaScript to work properly. Please enable it to take advantage of the complete set of features!

Skip to main page content

Add to Collections

Your saved search

Name of saved search:

Search terms:

Test search terms

Would you like email updates of new search results?

Yes
No

Email: (change)

Frequency:

Which day?

Which day?

Report format:

Send at most:

Send even when there aren't any new results

Optional text in email:

Your RSS Feed

. 1978 Aug 29;83(4):1347-53.

doi: 10.1016/0006-291x(78)91369-4.

Denaturation of cytochrome P-450 by cyclophosphamide metabolites

A J Marinello, H L Gurtoo, R F Struck, B Paul

PMID: 697865
DOI: 10.1016/0006-291x(78)91369-4

Denaturation of cytochrome P-450 by cyclophosphamide metabolites

A J Marinello et al. Biochem Biophys Res Commun. 1978.

. 1978 Aug 29;83(4):1347-53.

doi: 10.1016/0006-291x(78)91369-4.

Authors

A J Marinello, H L Gurtoo, R F Struck, B Paul

PMID: 697865
DOI: 10.1016/0006-291x(78)91369-4

No abstract available

PubMed Disclaimer

Similar articles

Cyclophosphamide modulates rat hepatic cytochrome P450 2C11 and steroid 5 alpha-reductase activity and messenger RNA levels through the combined action of acrolein and phosphoramide mustard.
Chang TK, Waxman DJ. Chang TK, et al. Cancer Res. 1993 Jun 1;53(11):2490-7. Cancer Res. 1993. PMID: 8495410
Comparison of the mutagenicity and teratogenicity of cyclophosphamide and its active metabolites, 4-hydroxycyclophosphamide, phosphoramide mustard, and acrolein.
Hales BF. Hales BF. Cancer Res. 1982 Aug;42(8):3016-21. Cancer Res. 1982. PMID: 7046914 No abstract available.
Effect of thiols on toxicity and carcinostatic activity of cyclophosphamide.
Gurtoo HL, Marinello AJ, Berrigan MJ, Bansal SK, Paul B, Pavelic ZP, Struck RF. Gurtoo HL, et al. Semin Oncol. 1983 Mar;10(1 Suppl 1):35-45. Semin Oncol. 1983. PMID: 6836326 No abstract available.
Metabolism of oxazaphosphorines.
Sladek NE. Sladek NE. Pharmacol Ther. 1988;37(3):301-55. doi: 10.1016/0163-7258(88)90004-6. Pharmacol Ther. 1988. PMID: 3290910 Review. No abstract available.
Oxazaphosphorines: new therapeutic strategies for an old class of drugs.
Giraud B, Hebert G, Deroussent A, Veal GJ, Vassal G, Paci A. Giraud B, et al. Expert Opin Drug Metab Toxicol. 2010 Aug;6(8):919-38. doi: 10.1517/17425255.2010.487861. Expert Opin Drug Metab Toxicol. 2010. PMID: 20446865 Review.

See all similar articles

Cited by

Suicidal destruction of cytochrome p-450 by ethynyl substituted compounds.
White IN. White IN. Pharm Res. 1984 Jul;1(4):141-8. doi: 10.1023/A:1016388306241. Pharm Res. 1984. PMID: 24277281
Isophosphoramide mustard, a metabolite of ifosfamide with activity against murine tumours comparable to cyclophosphamide.
Struck RF, Dykes DJ, Corbett TH, Suling WJ, Trader MW. Struck RF, et al. Br J Cancer. 1983 Jan;47(1):15-26. doi: 10.1038/bjc.1983.2. Br J Cancer. 1983. PMID: 6821629 Free PMC article.
Rescue of rats from large dose cyclophosphamide toxicity using protein A.
Ray PK, Dohadwala M, Bandyopadhyay SK, Canchanapan P, McLaughlin D. Ray PK, et al. Cancer Chemother Pharmacol. 1985;14(1):59-62. doi: 10.1007/BF00552727. Cancer Chemother Pharmacol. 1985. PMID: 3965160
Pharmacokinetics of high-dose cyclophosphamide in patients with metastatic bronchogenic carcinoma.
Wilkinson PM, O'Neill PA, Thatcher N, Lucas SB. Wilkinson PM, et al. Cancer Chemother Pharmacol. 1983;11(3):196-9. doi: 10.1007/BF00254204. Cancer Chemother Pharmacol. 1983. PMID: 6640827
Clinical pharmacokinetics of cyclophosphamide.
de Jonge ME, Huitema AD, Rodenhuis S, Beijnen JH. de Jonge ME, et al. Clin Pharmacokinet. 2005;44(11):1135-64. doi: 10.2165/00003088-200544110-00003. Clin Pharmacokinet. 2005. PMID: 16231966 Review.

See all "Cited by" articles

Publication types

Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions
Actions

Substances

Actions
Actions
Actions
Actions
Actions
Actions

LinkOut - more resources

Full Text Sources
- Elsevier Science