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. 1982 Mar-Apr;4(2):426-8.
doi: 10.1093/clinids/4.2.426.

Adverse reactions to trimethoprim-sulfamethoxazole in hospitalized patients

Adverse reactions to trimethoprim-sulfamethoxazole in hospitalized patients

H Jick. Rev Infect Dis. 1982 Mar-Apr.

Abstract

Of 1,121 hospitalized recipients of trimethoprim-sulfamethoxazole, 91 (8%) experienced reactions that were attributed to this drug. The most common adverse effects were gastrointestinal upset (3.9%) and skin reactions (3.3%). Serious toxicity attributable to the drug was rare.

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