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. 1982 Jul;22(1):162-4.
doi: 10.1128/AAC.22.1.162.

Pyridinium-2-azo-p-dimethylaniline chromophore, a new chromogenic cephalosporin for rapid beta-lactamase testing

J H Jorgensen, S A Crawford, G A Alexander

Pyridinium-2-azo-p-dimethylaniline chromophore, a new chromogenic cephalosporin for rapid beta-lactamase testing

J H Jorgensen et al. Antimicrob Agents Chemother. 1982 Jul.

Abstract

A new chromogenic cephalosporin, pyridinium-2-azo-p-dimethylaniline chromophore, was evaluated for use in a rapid paper strip or tube test for the detection of beta-lactamases from a variety of microorganisms. A 1-min pyridinium-2-azo-p-dimethylaniline chromophore paper strip test was found to be a convenient and accurate method for the detection of beta-lactamase-producing strains of Haemophilus influenzae and Neisseria gonorrhoeae, although it could not be relied upon to detect beta-lactamases produced by staphylococci, enteric organisms, or Bacteroides fragilis.

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