Ancylostoma caninum: immune response to and distribution pattern of larvae in mice with sensitized thymus and bone marrow cells

Abstract

Suspensions of thymus and bone marrow cells from Swiss albino donor mice infected with A. caninum larvae were injected separately or together into syngeneic, nonimmune recipients which were subsequently challenged with the larvae. The transfer of adoptive immunity through these cells has been confirmed and a cooperation and/or complementation between these two types was also observed. These sensitized cells helped the recipients in expelling and/or destroying the challenge larvae more effectively but had no remarkable effect on their distribution patterns.