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. 1980;54(2):201-4.
doi: 10.1007/BF00278972.

Regional assignment of the gene locus for steroid sulfatase

C R Müller, A Westerveld, B Migl, W Franke, H H Ropers

Regional assignment of the gene locus for steroid sulfatase

C R Müller et al. Hum Genet. 1980.

Abstract

The gene locus for steroid sulfatase, deficiency of which causes X-linked ichthyosis, is assigned to Xp11 leads to Xpter by analysis of 24 man-Chinese hamster somatic cell hybrids. High steroid sulfatase activity in a hybrid clone having retained only part of Xq is explained by demonstration of an additional late-replicating human X chromosome. This observation confirms previous evidence for noninactivation of the STS locus.

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