Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1980 Apr 11;208(4440):177-9.
doi: 10.1126/science.6987736.

Silicone rubber substrata: a new wrinkle in the study of cell locomotion

A K Harris, P Wild, D Stopak

Silicone rubber substrata: a new wrinkle in the study of cell locomotion

A K Harris et al. Science. .

Abstract

When tissue cells are cultured on very thin sheets of cross-linked silicone fluid, the traction forces the cells exert are made visible as elastic distortion and wrinkling of this substratum. Around explants this pattern of wrinkling closely resembles the "center effects" long observed in plasma clots and traditionally attributed to dehydration shrinkage.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources