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Review
. 1980 Jan 26;122(2):175-9.

Prostaglandin I2 (prostacyclin)

J G Kelton, M A Blajchman
Review

Prostaglandin I2 (prostacyclin)

J G Kelton et al. Can Med Assoc J. .

Abstract

Prostaglandin I2 (PGI2), or prostacyclin, is a recently discovered prostaglandin that affects many organ systems. It is both a potent inhibitor of platelet aggregation and a powerful vasodilator. The recent demonstration that it is the main prostaglandin synthesized by the blood vessel wall suggests that it may play an important role in limiting platelet-mediated thrombosis. However, despite considerable investigation, the exact physiological role of PGI2 has yet to be elucidated.

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References

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